Arbi-D 300/12.5mg Tablets – Irbesartan+Hydrochlorothiazide
Brand Name: Arbi-D
Generic Name: Irbesartan + Hydrochlorothiazide
Dosage Strength: 300mg Irbesartan + 12.5mg Hydrochlorothiazide
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 10 Tablets
Description and Usage:
Arbi-D (Irbesartan+Hydrochlorothiazide) 300/12.5mg Tablets are indicated for the treatment of hypertension (high blood pressure) in adults. This combination medication helps to lower blood pressure through complementary mechanisms of action.
- Irbesartan: Irbesartan is an angiotensin II receptor blocker (ARB) that works by blocking the binding of angiotensin II to its receptors, thereby causing vasodilation and lowering blood pressure.
- Hydrochlorothiazide: Hydrochlorothiazide is a thiazide diuretic that works by increasing the excretion of sodium and water by the kidneys, leading to decreased blood volume and reduced vascular resistance, which lowers blood pressure.
Description
Arbi-D 300/12.5mg Tablets represent a pharmaceutical combination of two active ingredients: Irbesartan and Hydrochlorothiazide.
This medication is primarily prescribed for the management of hypertension, a condition that affects millions worldwide.
By combining these two agents, Arbi-D aims to provide effective blood pressure control, thereby reducing the risk of cardiovascular complications.
In this article, we delve into the composition, mechanism of action, indications, dosage, side effects, and precautions associated with Arbi-D 300/12.5mg Tablets.
Composition and Mechanism of Action: Arbi-D 300/12.5mg Tablets contain two key components:
Irbesartan:
Irbesartan belongs to a class of medications known as angiotensin II receptor blockers (ARBs).
It works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow, leading to increased blood pressure.
By inhibiting this action, irbesartan helps blood vessels relax, thus lowering blood pressure.
Hydrochlorothiazide:
Hydrochlorothiazide is a thiazide diuretic, which works by increasing the excretion of sodium and water from the body through urine.
This leads to reduced fluid volume in the bloodstream and consequently lowers blood pressure.
The combination of these two agents in Arbi-D 300/12.5mg Tablets provides complementary mechanisms of action, resulting in a more effective reduction of blood pressure compared to either drug alone.
Indications:
Arbi-D 300/12.5mg Tablets are indicated for the treatment of hypertension (high blood pressure) in adults.
Hypertension is a significant risk factor for various cardiovascular diseases, including heart attack, stroke, and heart failure.
Controlling blood pressure with medications like Arbi-D can help reduce these risks and improve overall cardiovascular health.
Dosage:
The dosage of Arbi-D 300/12.5mg Tablets may vary depending on individual patient factors and the severity of hypertension.
It is essential to follow the prescribing physician’s instructions carefully.
Typically, the recommended starting dose is one tablet once daily, with adjustments made based on the patient’s response.
Side Effects:
Like all medications, Arbi-D 300/12.5mg Tablets can cause side effects, although not everyone experiences them.
Common side effects may include:
- Dizziness
- Fatigue
- Headache
- Nausea
- Diarrhea
- Hypotension (low blood pressure)
- Increased blood potassium levels (hyperkalemia)
- Electrolyte disturbances
- Muscle cramps
In rare cases, more severe side effects such as allergic reactions, kidney problems, or liver dysfunction may occur.
Patients experiencing any unusual or persistent side effects should seek medical attention promptly.
Precautions:
Before taking Arbi-D 300/12.5mg Tablets, patients should inform their healthcare provider about any pre-existing medical conditions, allergies, or medications they are taking.
It is essential to exercise caution in certain situations, including:
Pregnancy and breastfeeding:
Arbi-D is not recommended during pregnancy or breastfeeding, as it may harm the fetus or nursing infant.
Renal impairment:
Patients with impaired kidney function may require dosage adjustments or closer monitoring while taking Arbi-D.
Hepatic impairment:
Patients with liver disease should use Arbi-D with caution, as it may exacerbate liver dysfunction.
Electrolyte abnormalities:
Arbi-D can cause electrolyte disturbances, particularly in patients with conditions predisposing them to such imbalances, such as renal dysfunction or concurrent use of other medications affecting electrolyte levels.
Conclusion:
Arbi-D 300/12.5mg Tablets offer a combination therapy approach for the management of hypertension, incorporating the benefits of both Irbesartan and Hydrochlorothiazide.
By effectively lowering blood pressure, Arbi-D helps reduce the risk of cardiovascular complications associated with hypertension.
However, it is essential to use this medication under the guidance of a healthcare professional, adhere to prescribed dosages, and be vigilant for any potential side effects.
With proper monitoring and adherence to treatment, Arbi-D can be a valuable tool in promoting cardiovascular health and reducing the burden of hypertension-related diseases.
Buy: Arbi-D (Irbesartan+Hydrochlorothiazide) 150/12.5mg Tablets
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