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Brand Name: X-Plended

Generic Name: Rosuvastatin

Dosage Strength: 20mg

Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.

Packing: 10 Tablets

Description and Usage:

X-Plended (Rosuvastatin) 20mg Tablets are indicated for the treatment of hypercholesterolemia (elevated cholesterol levels) and dyslipidemia (abnormal lipid levels), including:

• Hypercholesterolemia: Elevated levels of total cholesterol and/or low-density lipoprotein cholesterol (LDL-C).
• Mixed dyslipidemia: Elevated levels of LDL-C, triglycerides, and low levels of high-density lipoprotein cholesterol (HDL-C).
• Homozygous familial hypercholesterolemia: An inherited condition causing extremely high levels of LDL-C.

Rosuvastatin belongs to a class of medications known as statins. It works by inhibiting the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis in the liver. By blocking this enzyme, Rosuvastatin reduces the production of cholesterol, leading to decreased levels of LDL-C (“bad” cholesterol) and triglycerides, and increased levels of HDL-C (“good” cholesterol).

Brand Name: X-Plended EZ

Generic Name: Rosuvastatin + Ezetimibe

Dosage Strength: 20mg Rosuvastatin + 10mg Ezetimibe

Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.

Packing: 10 Tablets

Description and Usage:

X-Plended EZ (Rosuvastatin+Ezetimibe) tablets are indicated for the treatment of hypercholesterolemia and mixed dyslipidemia, including:

• Elevated levels of low-density lipoprotein cholesterol (LDL-C)
• Elevated levels of total cholesterol
• Elevated levels of non-high-density lipoprotein cholesterol (non-HDL-C)
• Elevated levels of triglycerides (in combination with a statin)
• In patients with homozygous familial hypercholesterolemia (in combination with other lipid-lowering treatments)

• Rosuvastatin: Rosuvastatin is a statin medication that works by inhibiting the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis in the liver. By blocking this enzyme, Rosuvastatin reduces the production of cholesterol, leading to decreased levels of LDL-C (“bad” cholesterol) and triglycerides.
• Ezetimibe: Ezetimibe works by inhibiting the absorption of cholesterol in the small intestine, thereby reducing the amount of cholesterol that enters the bloodstream. It primarily inhibits the absorption of dietary cholesterol and cholesterol derived from bile.