Linamide (Lenalidomide in Pakistan) | 25 mg Capsule | Price Per Pack

Description

Lenalidomide in Pakistan | Linamide Brand Available Online

• Brand Name: Linamide
• Generic Name: Lenalidomide
• Strength: 25 mg Capsules
• Manufacturer: Beacon Pharmaceutical
• Pack Size: 18 Capsules
• Price in Pakistan: PKR 27,853

Lenalidomide in Pakistan:

Linamide (Lenalidomide) 25 mg is an oral immunomodulatory and anti-cancer medication used in the treatment of various hematological malignancies.

It works by enhancing immune system activity, inhibiting abnormal cell growth, and promoting anti-tumor responses. It is commonly used in combination with other medicines such as dexamethasone.

Key Indications of Lenalidomide:

Linamide is prescribed for the management of:

1. Multiple Myeloma (MM)

• First-line therapy in combination with dexamethasone.

• Used post-stem cell transplantation as maintenance therapy.

2. Myelodysplastic Syndromes (MDS)

• Especially effective in MDS with deletion 5q cytogenetic abnormality.

• Helps reduce transfusion requirements.

3. Mantle Cell Lymphoma (MCL)

• Used in relapsed or refractory cases.

4. Follicular Lymphoma / Marginal Zone Lymphoma

• In combination with rituximab.

5. Certain Off-label Uses (Physician-directed)

• Relapsed lymphomas

• Chronic lymphocytic leukemia (in selected patients)

How Linamide (Lenalidomide) Works?

Lenalidomide is an immunomodulatory agent (IMiD) that:

• Enhances T-cell and NK-cell activity

• Inhibits cytokines promoting cancer cell growth

• Reduces angiogenesis (formation of new vessels that feed tumors)

• Triggers cancer cell death

Dosage & Administration

Always follow the oncologist’s instructions. Dosage varies by condition and kidney function.

1. Multiple Myeloma

• Standard dose: 25 mg once daily

• Schedule: Days 1–21 of a 28-day cycle

• Usually given with dexamethasone

2. MDS (5q-Deletion)

• Dose: 10 mg once daily

• Continue until disease progression or unacceptable toxicity

3. Mantle Cell Lymphoma (MCL)

• Dose: 25 mg once daily

• Schedule: Days 1–21 of a 28-day cycle

4. Follicular/Marginal Zone Lymphoma

• Dose: 20–25 mg once daily

• In combination with rituximab

Dose Adjustment in Kidney Disease

• Moderate renal impairment: 10 mg daily

• Severe renal impairment: 15 mg every other day

• Dialysis patients: 5 mg daily after dialysis

Dose reduction is needed in case of side effects like neutropenia or thrombocytopenia.

Side Effects of Lenalidomide in Pakistan:

Like all anti-cancer agents, Linamide may cause side effects. Some are serious and require immediate medical attention.

Common Side Effects

• Fatigue

• Constipation or diarrhea

• Rash

• Back or joint pain

• Nausea

• Low blood counts (neutropenia, anemia, thrombocytopenia)

Serious Side Effects

• Severe neutropenia (risk of infection)

• Blood clots (DVT/PE)

• Liver function abnormalities

• Allergic reactions

• Secondary malignancies (rare)

• Severe skin reactions (Stevens–Johnson Syndrome)

• Birth defects if taken during pregnancy

Linamide Contraindications

• Pregnancy (absolute contraindication – high risk of birth defects)

• Known hypersensitivity to lenalidomide

• Breastfeeding

Linamide Precautions

• Use reliable contraception (men and women)

• Regular blood tests for CBC, liver, and kidney function

• Monitor for signs of thrombosis

• Dose reduction required in renal impairment

• Avoid donating blood or sperm during treatment

Storage

• Store at room temperature (below 25°C)

• Keep away from moisture and direct sunlight

• Keep out of reach of children

Disclaimer

This product description is for educational purposes only. Linamide (Lenalidomide) is a prescription-only anti-cancer medication that must be used strictly under the supervision of an oncologist or qualified healthcare professional. Dosage and treatment plans vary by individual condition. Do not self-medicate. Consult your doctor before starting or stopping any medication.