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₨ 250Discover the Power of Fenhil 10 mg (Finerenone) Experience a breakthrough in heart and kidney health with Fenhil 10 mg (Finerenone), a cutting-edge non-steroidal mineralocorticoid receptor antagonist (MRA). This innovative medication is specifically designed to target and manage the complications associated with diabetic kidney disease and heart failure, providing patients with a new avenue toward…
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Brand Name: EvoFix
Generic Name: Cefixime
Dosage Strength: 400mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 10 Capsules
Description and Usage:
EvoFix (Cefixime) 400mg Capsules are indicated for the treatment of various bacterial infections caused by susceptible organisms, including:
- Upper respiratory tract infections, such as otitis media (middle ear infection), sinusitis, and pharyngitis (sore throat)
- Lower respiratory tract infections, such as bronchitis and community-acquired pneumonia
- Urinary tract infections, including cystitis (bladder infection) and pyelonephritis (kidney infection)
- Uncomplicated gonorrhea
Cefixime is a bactericidal antibiotic that works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) located on the bacterial cell wall, which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. This leads to cell wall instability and ultimately cell lysis, resulting in the death of susceptible bacteria.
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₨ 435Brand Name: Arbi-D
Generic Name: Irbesartan + Hydrochlorothiazide
Dosage Strength: 150mg Irbesartan + 12.5mg Hydrochlorothiazide
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 10 Tablets
Description and Usage:
Arbi-D (Irbesartan+Hydrochlorothiazide) 150/12.5mg Tablets are indicated for the treatment of hypertension (high blood pressure) in adults. This combination medication helps to lower blood pressure through complementary mechanisms of action.
- Irbesartan: Irbesartan is an angiotensin II receptor blocker (ARB) that works by blocking the binding of angiotensin II to its receptors, thereby causing vasodilation and lowering blood pressure.
- Hydrochlorothiazide: Hydrochlorothiazide is a thiazide diuretic that works by increasing the excretion of sodium and water by the kidneys, leading to decreased blood volume and reduced vascular resistance, which lowers blood pressure.
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Brand Name: Arbi
Generic Name: Irbesartan
Dosage Strength: 300mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 10 Tablets
Description and Usage:
Arbi (Irbesartan) 300mg Tablets are indicated for the following conditions:
- Hypertension (high blood pressure): Irbesartan helps to lower blood pressure by blocking the action of angiotensin II, a hormone that narrows blood vessels and increases blood pressure.
- Diabetic nephropathy: Irbesartan may be used to slow the progression of kidney damage in patients with type 2 diabetes and high blood pressure.
Irbesartan is an angiotensin II receptor blocker (ARB) that selectively blocks the binding of angiotensin II to its receptors. By blocking the action of angiotensin II, irbesartan relaxes blood vessels, leading to vasodilation and lowering of blood pressure. It also helps to reduce the workload on the heart and protect the kidneys from damage.
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Brand Name: Inosita Plus
Generic Name: Sitagliptin + Metformin HCl
Dosage Strength: 50mg Sitagliptin + 850mg Metformin HCl
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 28 Tablets
Description and Usage:
Inosita Plus (Sitagliptin+Metformin HCl) 50/850mg Tablets are indicated for the management of type 2 diabetes mellitus in adults. This combination medication helps to control blood sugar levels by multiple mechanisms of action.
- Sitagliptin: Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by inhibiting the enzyme DPP-4, which in turn increases the levels of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones stimulate insulin release from pancreatic beta cells and decrease glucagon secretion from pancreatic alpha cells, thereby reducing blood glucose levels.
- Metformin Hydrochloride: Metformin is a biguanide medication that works primarily by decreasing hepatic glucose production and increasing peripheral glucose uptake and utilization. It also improves insulin sensitivity in peripheral tissues such as muscle and adipose tissue.
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Brand Name: Inosita Plus
Generic Name: Sitagliptin + Metformin HCl
Dosage Strength: 50mg Sitagliptin + 500mg Metformin HCl
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 28 Tablets
Description and Usage:
Inosita Plus (Sitagliptin+Metformin HCl) 50/500mg Tablets are indicated for the management of type 2 diabetes mellitus in adults. This combination medication helps to control blood sugar levels by multiple mechanisms of action.
- Sitagliptin: Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by inhibiting the enzyme DPP-4, which in turn increases the levels of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones stimulate insulin release from pancreatic beta cells and decrease glucagon secretion from pancreatic alpha cells, thereby reducing blood glucose levels.
- Metformin Hydrochloride: Metformin is a biguanide medication that works primarily by decreasing hepatic glucose production and increasing peripheral glucose uptake and utilization. It also improves insulin sensitivity in peripheral tissues such as muscle and adipose tissue.
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₨ 610Brand Name: ?
Generic Name: Vildagliptin + Metformin HCl
Dosage Strength: 50mg Vildagliptin + 1000mg Metformin HCl
Manufacturer: Pharmaceutical (Pvt) Ltd.
Packing: 14 Tablets
Description and Usage:
Galvecta Plus (Vildagliptin+Metformin HCl) 50/1000mg Tablets are indicated for the management of type 2 diabetes mellitus in adults. This combination medication helps to control blood sugar levels by multiple mechanisms of action.
- Vildagliptin: Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by inhibiting the enzyme DPP-4, which in turn increases the levels of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones stimulate insulin release from pancreatic beta cells and decrease glucagon secretion from pancreatic alpha cells, thereby reducing blood glucose levels.
- Metformin Hydrochloride: Metformin is a biguanide medication that works primarily by decreasing hepatic glucose production and increasing peripheral glucose uptake and utilization. It also improves insulin sensitivity in peripheral tissues such as muscle and adipose tissue.
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₨ 580Brand Name: Galvecta Plus
Generic Name: Vildagliptin + Metformin HCl
Dosage Strength: 50mg Vildagliptin + 500mg Metformin HCl
Manufacturer: Pharmaceutical (Pvt) Ltd.
Packing: 14 Tablets
Description and Usage:
Galvecta Plus (Vildagliptin+Metformin HCl) 50/500mg Tablets are indicated for the management of type 2 diabetes mellitus in adults. This combination medication helps to control blood sugar levels by multiple mechanisms of action.
- Vildagliptin: Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by inhibiting the enzyme DPP-4, which in turn increases the levels of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones stimulate insulin release from pancreatic beta cells and decrease glucagon secretion from pancreatic alpha cells, thereby reducing blood glucose levels.
- Metformin Hydrochloride: Metformin is a biguanide medication that works primarily by decreasing hepatic glucose production and increasing peripheral glucose uptake and utilization. It also improves insulin sensitivity in peripheral tissues such as muscle and adipose tissue.
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Brand Name: Zilero
Generic Name: Apixaban
Dosage Strength: 2.5mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 30 Tablets
Description and Usage:
Zilero (Apixaban) 2.5mg Tablets are indicated for the following conditions:
- Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation
- Treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE)
- Prevention of recurrent DVT and PE in patients who have completed initial treatment
Apixaban is a selective inhibitor of factor Xa, an enzyme involved in the coagulation cascade. By inhibiting factor Xa, apixaban prevents the formation of thrombin, which is crucial for blood clot formation. This anticoagulant effect reduces the risk of blood clot formation and helps prevent thromboembolic events.
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Brand Name: Duzalta
Generic Name: Duloxetine HCl
Dosage Strength: 60mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 14 Tablets
Description and Usage:
Duzalta (Duloxetine) 60mg Tablets are indicated for the treatment of various conditions, including:
- Major depressive disorder (MDD): A mood disorder characterized by persistent feelings of sadness, hopelessness, and loss of interest or pleasure in usual activities.
- Generalized anxiety disorder (GAD): A mental health condition characterized by excessive and uncontrollable worry about everyday events and activities.
- Fibromyalgia: A chronic pain disorder characterized by widespread musculoskeletal pain, fatigue, and tenderness in specific areas of the body.
- Chronic musculoskeletal pain: Chronic pain conditions such as chronic lower back pain, osteoarthritis, or chronic pain due to medical conditions.
Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) medication that works by increasing the levels of serotonin and norepinephrine in the brain. These neurotransmitters play a role in regulating mood, emotions, and pain perception. By inhibiting their reuptake, duloxetine helps to alleviate symptoms of depression, anxiety, and pain.
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Brand Name: Duzalta
Generic Name: Duloxetine HCl
Dosage Strength: 30mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 14 Tablets
Description and Usage:
Duzalta (Duloxetine) 30mg Tablets are indicated for the treatment of various conditions, including:
- Major depressive disorder (MDD): A mood disorder characterized by persistent feelings of sadness, hopelessness, and loss of interest or pleasure in usual activities.
- Generalized anxiety disorder (GAD): A mental health condition characterized by excessive and uncontrollable worry about everyday events and activities.
- Fibromyalgia: A chronic pain disorder characterized by widespread musculoskeletal pain, fatigue, and tenderness in specific areas of the body.
- Chronic musculoskeletal pain: Chronic pain conditions such as chronic lower back pain, osteoarthritis, or chronic pain due to medical conditions.
Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) medication that works by increasing the levels of serotonin and norepinephrine in the brain. These neurotransmitters play a role in regulating mood, emotions, and pain perception. By inhibiting their reuptake, duloxetine helps to alleviate symptoms of depression, anxiety, and pain.
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Brand Name: Zibes
Generic Name: Bisoprolol Fumarate
Dosage Strength: 2.5mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 14 Tablets
Description and Usage:
Zibes (Bisoprolol Fumarate) 2.5mg Tablets are indicated for the management of various cardiovascular conditions, including:
- Hypertension (high blood pressure)
- Chronic stable angina (chest pain)
- Heart failure with reduced ejection fraction
Bisoprolol is a beta-blocker medication that works by blocking the action of catecholamines (such as adrenaline) on beta-adrenergic receptors in the heart and blood vessels. By blocking these receptors, bisoprolol reduces the heart rate, decreases myocardial oxygen demand, and lowers blood pressure, thereby improving symptoms and outcomes in various cardiovascular conditions.
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Brand Name: X-Plended EZ
Generic Name: Rosuvastatin + Ezetimibe
Dosage Strength: 20mg Rosuvastatin + 10mg Ezetimibe
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 10 Tablets
Description and Usage:
X-Plended EZ (Rosuvastatin+Ezetimibe) tablets are indicated for the treatment of hypercholesterolemia and mixed dyslipidemia, including:
- Elevated levels of low-density lipoprotein cholesterol (LDL-C)
- Elevated levels of total cholesterol
- Elevated levels of non-high-density lipoprotein cholesterol (non-HDL-C)
- Elevated levels of triglycerides (in combination with a statin)
- In patients with homozygous familial hypercholesterolemia (in combination with other lipid-lowering treatments)
- Rosuvastatin: Rosuvastatin is a statin medication that works by inhibiting the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis in the liver. By blocking this enzyme, Rosuvastatin reduces the production of cholesterol, leading to decreased levels of LDL-C (“bad” cholesterol) and triglycerides.
- Ezetimibe: Ezetimibe works by inhibiting the absorption of cholesterol in the small intestine, thereby reducing the amount of cholesterol that enters the bloodstream. It primarily inhibits the absorption of dietary cholesterol and cholesterol derived from bile.
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₨ 290Brand Name: X-Plended EZ
Generic Name: Rosuvastatin + Ezetimibe
Dosage Strength: 5mg Rosuvastatin + 10mg Ezetimibe
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 10 Tablets
Description and Usage:
X-Plended EZ (Rosuvastatin+Ezetimibe) tablets are indicated for the treatment of hypercholesterolemia and mixed dyslipidemia, including:
- Elevated levels of low-density lipoprotein cholesterol (LDL-C)
- Elevated levels of total cholesterol
- Elevated levels of non-high-density lipoprotein cholesterol (non-HDL-C)
- Elevated levels of triglycerides (in combination with a statin)
- In patients with homozygous familial hypercholesterolemia (in combination with other lipid-lowering treatments)
- Rosuvastatin: Rosuvastatin is a statin medication that works by inhibiting the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis in the liver. By blocking this enzyme, Rosuvastatin reduces the production of cholesterol, leading to decreased levels of LDL-C (“bad” cholesterol) and triglycerides.
- Ezetimibe: Ezetimibe works by inhibiting the absorption of cholesterol in the small intestine, thereby reducing the amount of cholesterol that enters the bloodstream. It primarily inhibits the absorption of dietary cholesterol and cholesterol derived from bile.
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Brand Name: X-Plended
Generic Name: Rosuvastatin
Dosage Strength: 20mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 10 Tablets
Description and Usage:
X-Plended (Rosuvastatin) 20mg Tablets are indicated for the treatment of hypercholesterolemia (elevated cholesterol levels) and dyslipidemia (abnormal lipid levels), including:
- Hypercholesterolemia: Elevated levels of total cholesterol and/or low-density lipoprotein cholesterol (LDL-C).
- Mixed dyslipidemia: Elevated levels of LDL-C, triglycerides, and low levels of high-density lipoprotein cholesterol (HDL-C).
- Homozygous familial hypercholesterolemia: An inherited condition causing extremely high levels of LDL-C.
Rosuvastatin belongs to a class of medications known as statins. It works by inhibiting the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis in the liver. By blocking this enzyme, Rosuvastatin reduces the production of cholesterol, leading to decreased levels of LDL-C (“bad” cholesterol) and triglycerides, and increased levels of HDL-C (“good” cholesterol).
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₨ 477Brand Name: X-Plended
Generic Name: Rosuvastatin
Dosage Strength: 10mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 10 Tablets
Description and Usage:
X-Plended (Rosuvastatin) 10mg Tablets are indicated for the treatment of hypercholesterolemia (elevated cholesterol levels) and dyslipidemia (abnormal lipid levels), including:
- Hypercholesterolemia: Elevated levels of total cholesterol and/or low-density lipoprotein cholesterol (LDL-C).
- Mixed dyslipidemia: Elevated levels of LDL-C, triglycerides, and low levels of high-density lipoprotein cholesterol (HDL-C).
- Homozygous familial hypercholesterolemia: An inherited condition causing extremely high levels of LDL-C.
Rosuvastatin belongs to a class of medications known as statins. It works by inhibiting the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis in the liver. By blocking this enzyme, Rosuvastatin reduces the production of cholesterol, leading to decreased levels of LDL-C (“bad” cholesterol) and triglycerides, and increased levels of HDL-C (“good” cholesterol).
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Brand Name: Orslim
Generic Name: Orlistat
Dosage Strength: 120mg
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 30 Capsules
Description and Usage:
Orslim (Orlistat) 120mg Capsules are indicated for weight management in overweight or obese adults, in conjunction with a reduced-calorie diet and lifestyle modifications. Orlistat works by inhibiting the absorption of dietary fats, thereby reducing caloric intake and promoting weight loss.
Orlistat works by inhibiting the activity of pancreatic lipase, an enzyme responsible for breaking down dietary fats into absorbable forms. By inhibiting this enzyme, Orlistat prevents the hydrolysis of triglycerides into absorbable fatty acids and monoglycerides. As a result, undigested fats are excreted in the feces, leading to reduced calorie absorption and weight loss.
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Brand Name: Paridopa
Generic Name: Levodopa + Carbidopa + Entacapone
Dosage Strength: 200mg Levodopa + 50mg Carbidopa + 200mg Entacapone
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 30 Tablets
Description and Usage:
Paridopa (Levodopa+Carbidopa+Entacapone) tablets are indicated for the treatment of Parkinson’s disease in patients experiencing motor fluctuations. Levodopa is converted to dopamine in the brain, helping to replenish dopamine levels, while Carbidopa helps prevent the breakdown of levodopa before it reaches the brain. Entacapone prolongs the effects of levodopa by inhibiting the enzyme that breaks it down, thereby improving motor symptoms of Parkinson’s disease.
- Levodopa: Levodopa is a precursor of dopamine. In Parkinson’s disease, there is a deficiency of dopamine, a neurotransmitter involved in movement control. Levodopa crosses the blood-brain barrier and is converted into dopamine in the brain, thereby alleviating motor symptoms.
- Carbidopa: Carbidopa inhibits the peripheral decarboxylation of levodopa, ensuring more levodopa reaches the brain and reducing peripheral side effects.
- Entacapone: Entacapone inhibits the enzyme catechol-O-methyltransferase (COMT), which breaks down levodopa in the peripheral tissues. By inhibiting this enzyme, entacapone prolongs the effects of levodopa in the brain, thereby reducing motor fluctuations in Parkinson’s disease.
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Brand Name: Paridopa
Generic Name: Levodopa + Carbidopa + Entacapone
Dosage Strength: 100mg Levodopa + 25mg Carbidopa + 200mg Entacapone
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 30 Tablets
Description and Usage:
Paridopa (Levodopa+Carbidopa+Entacapone) tablets are indicated for the treatment of Parkinson’s disease in patients experiencing motor fluctuations. Levodopa is converted to dopamine in the brain, helping to replenish dopamine levels, while Carbidopa helps prevent the breakdown of levodopa before it reaches the brain. Entacapone prolongs the effects of levodopa by inhibiting the enzyme that breaks it down, thereby improving motor symptoms of Parkinson’s disease.
- Levodopa: Levodopa is a precursor of dopamine. In Parkinson’s disease, there is a deficiency of dopamine, a neurotransmitter involved in movement control. Levodopa crosses the blood-brain barrier and is converted into dopamine in the brain, thereby alleviating motor symptoms.
- Carbidopa: Carbidopa inhibits the peripheral decarboxylation of levodopa, ensuring more levodopa reaches the brain and reducing peripheral side effects.
- Entacapone: Entacapone inhibits the enzyme catechol-O-methyltransferase (COMT), which breaks down levodopa in the peripheral tissues. By inhibiting this enzyme, entacapone prolongs the effects of levodopa in the brain, thereby reducing motor fluctuations in Parkinson’s disease.
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Brand Name: Opt-D
Generic Name: Cholecalciferol (Vitamin D3)
Dosage Strength: 25000IU
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 4 Softgel Capsules
Description and Usage:
Opt-D capsules containing Cholecalciferol, commonly known as Vitamin D3, are used to treat or prevent vitamin D deficiency. Cholecalciferol (Vitamin D3) is synthesized in the skin upon exposure to sunlight or obtained from dietary sources. It undergoes hydroxylation in the liver and kidneys to form the biologically active form of vitamin D, calcitriol. Calcitriol acts on the intestines, kidneys, and bones to regulate calcium and phosphate metabolism, promoting bone mineralization and overall bone health.
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Brand Name: Opt-D
Generic Name: Cholecalciferol (Vitamin D3)
Dosage Strength: 100000IU
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 1 Softgel Capsules
Description and Usage:
Opt-D capsules containing Cholecalciferol, commonly known as Vitamin D3, are used to treat or prevent vitamin D deficiency. Cholecalciferol (Vitamin D3) is synthesized in the skin upon exposure to sunlight or obtained from dietary sources. It undergoes hydroxylation in the liver and kidneys to form the biologically active form of vitamin D, calcitriol. Calcitriol acts on the intestines, kidneys, and bones to regulate calcium and phosphate metabolism, promoting bone mineralization and overall bone health.
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Brand Name: Opt-D
Generic Name: Cholecalciferol (Vitamin D3)
Dosage Strength: 200000IU
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 1 Softgel Capsules
Description and Usage:
Opt-D capsules containing Cholecalciferol, commonly known as Vitamin D3, are used to treat or prevent vitamin D deficiency. Cholecalciferol (Vitamin D3) is synthesized in the skin upon exposure to sunlight or obtained from dietary sources. It undergoes hydroxylation in the liver and kidneys to form the biologically active form of vitamin D, calcitriol. Calcitriol acts on the intestines, kidneys, and bones to regulate calcium and phosphate metabolism, promoting bone mineralization and overall bone health.
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Brand Name: Inosita Plus XR
Generic Name: Sitagliptin + Metformin HCl
Dosage Strength: 100mg Sitagliptin + 1000mg Metformin HCl
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 14 Tablets Extended Release
Description and Usage:
Inosita Plus XR tablets combine two active ingredients: Sitagliptin and Metformin Hydrochloride (HCl). This combination medication is used in the treatment of type 2 diabetes mellitus to help control blood sugar levels.
Inosita Plus XR (Sitagliptin+Metformin HCl) tablets are indicated for the management of type 2 diabetes mellitus in adults. This medication helps to control blood sugar levels by multiple mechanisms of action, including increasing insulin secretion and reducing hepatic glucose production.
- Sitagliptin: Inhibits the enzyme dipeptidyl peptidase-4 (DPP-4), leading to increased levels of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This results in enhanced insulin secretion and decreased glucagon release, ultimately reducing blood glucose levels.
- Metformin Hydrochloride: Decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
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₨ 1,255Brand Name: Inosita Plus XR
Generic Name: Sitagliptin + Metformin HCl
Dosage Strength: 50mg Sitagliptin + 1000mg Metformin HCl
Manufacturer: PharmaEvo Pharmaceutical (Pvt) Ltd.
Packing: 14 Tablets Extended Release
Description and Usage:
Inosita Plus XR tablets combine two active ingredients: Sitagliptin and Metformin Hydrochloride (HCl). This combination medication is used in the treatment of type 2 diabetes mellitus to help control blood sugar levels.
Inosita Plus XR (Sitagliptin+Metformin HCl) tablets are indicated for the management of type 2 diabetes mellitus in adults. This medication helps to control blood sugar levels by multiple mechanisms of action, including increasing insulin secretion and reducing hepatic glucose production.
- Sitagliptin: Inhibits the enzyme dipeptidyl peptidase-4 (DPP-4), leading to increased levels of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This results in enhanced insulin secretion and decreased glucagon release, ultimately reducing blood glucose levels.
- Metformin Hydrochloride: Decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.